Language Visual : an ontological use case
نویسندگان
چکیده
Synthetic Biology Open Language (SBOL) is a data exchange standard for the specification of forward engineered genetic designs (Galdzicki 2012). SBOL Visual is the graphical counterpart to SBOL, used to represent designs in a human readable manner. The central element in the SBOL data model is the DNA Component, which represents the design of a contiguous piece of DNA. DNA Components have an assigned functional role, generally referred to as ‘part type’ among synthetic biologists and which is analogous to the feature keys in annotated DNA sequences. SBOL exploits this similarity by requiring that part types be a term from the Sequence Ontology (SO) a pre-existing and widely used project for mapping DNA sequence annotation features onto an ontology framework (Eilbeck 2005). SBOL Visual consists of a set of symbols that can be used to graphically represent genetic designs (Quinn 2013). Each symbol represents one or more terms in the SO. In SBOL Visual, a DNA Component is represented visually by the symbol that represents its SO term. SBOL Visual symbols are an open-source and community-agreed collection of pictograms, intended to cover that subset of the SO relevant to genetic parts frequently used by synthetic biologists---at present 20 community-agreed pictograms. As the community and technology continue to develop, significant growth of the symbol set is expected. Ongoing efforts to enable such growth include development of a process for community members to propose new symbols and have them incorporated into the standard.
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تاریخ انتشار 2013